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RG 14620
CAS No. 136831-49-7
RG 14620 ( RG 14620; TYRPHOSTIN RG 14620. )
Catalog No. M17976 CAS No. 136831-49-7
RG14620 is an epidermal growth factor receptor (EGFR) inhibitor.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 27 | In Stock |
|
| 5MG | 43 | In Stock |
|
| 10MG | 63 | In Stock |
|
| 25MG | 125 | In Stock |
|
| 50MG | 245 | In Stock |
|
| 100MG | 410 | In Stock |
|
| 500MG | 888 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRG 14620
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NoteResearch use only, not for human use.
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Brief DescriptionRG14620 is an epidermal growth factor receptor (EGFR) inhibitor.
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DescriptionRG-14620 is an EGFR inhibitor. It is a non-phenolic tyrphostin analog, which is selective for the EGF receptor and long acting. It inhibits EGF-stimulated HER14 cell proliferation (IC50=3 μM) as well as tumor growth in vivo.
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SynonymsRG 14620; TYRPHOSTIN RG 14620.
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PathwayOthers
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TargetOther Targets
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RecptorHER14 colony formation; HER14 DNA synthesis
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number136831-49-7
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Formula Weight275.13
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Molecular FormulaC14H8Cl2N2
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Purity98%
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SolubilityDMSO : ≥ 26 mg/mL; 94.50 mM
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SMILESc1cc(cnc1)/C(=C\c1cc(cc(c1)Cl)Cl)/C#N
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Chemical Name(E)-3-(3,5-dichlorophenyl)-2-(pyridin-3-yl)acrylonitrile
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Yoneda T,et al. Cancer Res. 1991 Aug 15;51(16):4430-5.
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